1: 5'-chloro-3,5-dimethyl-2'-(piperazin-1-yl)-2,4'-bipyridine With 4-methyl-morpholine; benzotriazol-1-ol in dichloromethane T=20°C; 0.5 h; 2: 3-(methylsulfonyl)propanoic acid With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=20°C; 18 h;