1: (3,4-methylenedioxyphenyl) phenyl methanone oxime With sodium hydride in ethylene glycol dimethyl ether
T=20°C; Substitution; deprotonation; 0.5 h;
2: (4-bromomethyl-phenyl)-acetic acid in ethylene glycol dimethyl ether
Alkylation; 18 h; Heating; Title compound not separated from byproducts;
参考文献
De A. Reis, Andre L.; Ormelli, Claudia B.; Miranda, Ana L.P.; Fraga, Carlos A.M.; Barreiro, Eliezer J.
Pharmaceutica Acta Helvetiae, 1999 , vol. 74, # 1 p. 19 - 28
Flack, Stephen S.; Chaumette, Jean-Louis; Kilburn, Jeremy D.; Langley, G. John; Webster, Michael
Journal of the Chemical Society, Chemical Communications, 1993 , # 4 p. 399 - 401
Flack, Stephen S.; Chaumette, Jean-Louis; Kilburn, Jeremy D.; Langley, G. John; Webster, Michael
Journal of the Chemical Society, Chemical Communications, 1993 , # 4 p. 399 - 401
