4-(二甲基氨基)-6-甲基-2(1H)-吡啶酮合成路线 （共 3 条）
反应条件
phosphoric acid T=150 - 160°C; 1.5 h;
参考文献
Mezentseva, M. V.; Faermark, I. F.; Kuleshova, E. F.; Anisimova, O. S.; Shvarts, G. Ya.; et al.
Pharmaceutical Chemistry Journal, 1991 , vol. 25, # 9 p. 623 - 628
Khimiko-Farmatsevticheskii Zhurnal, 1991 , vol. 25, # 9 p. 29 - 33
反应条件
1: 89.6 percent / POCl3, DMF / toluene / 6 h / Heating 2: 87.5 percent / alcoholic NH3 / 9 h / 220 °C 3: 57 percent / 100percent H3PO4 / 1.5 h / 150 - 160 °C View Scheme
参考文献
Mezentseva, M. V.; Faermark, I. F.; Kuleshova, E. F.; Anisimova, O. S.; Shvarts, G. Ya.; et al.
Pharmaceutical Chemistry Journal, 1991 , vol. 25, # 9 p. 623 - 628
Khimiko-Farmatsevticheskii Zhurnal, 1991 , vol. 25, # 9 p. 29 - 33
反应条件
1: 19.1 percent / dimethylformamide / 2 h / Heating 2: 89.6 percent / POCl3, DMF / toluene / 6 h / Heating 3: 87.5 percent / alcoholic NH3 / 9 h / 220 °C 4: 57 percent / 100percent H3PO4 / 1.5 h / 150 - 160 °C View Scheme
参考文献
Mezentseva, M. V.; Faermark, I. F.; Kuleshova, E. F.; Anisimova, O. S.; Shvarts, G. Ya.; et al.
Pharmaceutical Chemistry Journal, 1991 , vol. 25, # 9 p. 623 - 628
Khimiko-Farmatsevticheskii Zhurnal, 1991 , vol. 25, # 9 p. 29 - 33
