1: 1.) NaNO2, aq. HCl, 2.) NaBF4 2: xylene / Heating View Scheme

1: 1.) NaNO2, aq. HCl, 2.) NaBF4 2: xylene / Heating 3: 1.) Mg, 2.) CuCl / 1.) diethyl ether, reflux, 2h, 2.) -17 deg C 4: 87 percent / 2 M aq. NaOH 5: 52 percent / polyphosphoric acid / 0.13 h / 90 °C 6: 54 percent / hydroxylamine hydrochloride, NaOH / ethanol View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '2037554', constants.ctx, '0')">sulfuric acid</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '385737', constants.ctx, '0')">acetic anhydride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '506007', constants.ctx, '0')">acetic acid</a> <br />T=60 - 95&deg;C;&nbsp;0.5&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 69 percent / AlCl₃ / cyclohexane / 0.25 h / Heating<br />2: 94 percent / Clemmensen procedure<br />3: 100 percent / PPA / 0.25 h / 90 &deg;C<br />4: hydroxylamine hydrochloride, NaOH / ethanol; H₂O / Heating<br />5: 60 percent / conc.H₂SO₄, acetic anhydride / acetic acid / 0.5 h / 60 - 95 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: hydroxylamine hydrochloride, NaOH / ethanol; H₂O / Heating<br />2: 60 percent / conc.H₂SO₄, acetic anhydride / acetic acid / 0.5 h / 60 - 95 &deg;C<br /> <br /> &nbsp;