反应条件
1.1: ozone / methanol; dichloromethane / 0.75 h / -78 °C 1.2: 20 °C 2.1: dihydrogen peroxide; sodium hydroxide / 1,4-dioxane; water / 0.17 h / 0 °C 3.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C 4.1: pyridine / tetrahydrofuran / 0.17 h / -40 °C 4.2: 20 h / -40 - 20 °C 5.1: Jone's reagent / acetone / 0.25 h / 0 - 20 °C 5.2: 1.5 h 6.1: lithium hydroxide hydrate / methanol; water / 0.5 h / Reflux 7.1: ammonia; lithium / tetrahydrofuran / 0.5 h / -78 °C View Scheme
参考文献
Luo, Zhi; Zhou, Bing; Li, Yuanchao
Organic Letters, 2012 , vol. 14, # 10 p. 2540 - 2543