1.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 20 °C 2.1: ozone / methanol; dichloromethane / 0.75 h / -78 °C 2.2: 20 °C 3.1: dihydrogen peroxide; sodium hydroxide / 1,4-dioxane; water / 0.17 h / 0 °C 4.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C 5.1: pyridine / tetrahydrofuran / 0.17 h / -40 °C 5.2: 20 h / -40 - 20 °C 6.1: Jone's reagent / acetone / 0.25 h / 0 - 20 °C 6.2: 1.5 h 7.1: lithium hydroxide hydrate / methanol; water / 0.5 h / Reflux 8.1: ammonia; lithium / tetrahydrofuran / 0.5 h / -78 °C View Scheme