1: (pyridin-3-yl)acetylene With 2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride T=50°C; 2: (E)-3-[[(trifluoromethyl)sulfonyl]oxy]-2-butenoic acid ethyl ester With triphenyl-arsane; tris(dibenzylideneacetone)dipalladium(0) chloroform complex in N,N-dimethyl-formamide T=20°C; Stille coupling reaction;

1.1: Ph3P 1.2: nBuLi 2.1: Bu3SnH; AIBN / 50 °C 2.2: AsPh3 / Pd2(dba)3*CHCl3 / dimethylformamide / 20 °C View Scheme

T=100 - 145°C; 1 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;