(S)-1-叔丁氧羰基-2-甲基吡咯烷合成路线 (共 13 条)
反应条件
sec.-butyllithium; (-)-sparteine 1.) Et2O, -78 deg C, 6 h, 2.) Et2O, from -78 deg C to RT; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 116, # 8 p. 3231 - 3239
反应条件
1: (+)-sparteine / tert-butyl methyl ether; cyclohexane / 2.17 h / -78 °C 2: tert-butyl methyl ether; cyclohexane View Scheme
参考文献
WO2008/73825 A1, ;
WO 2008/073825 A1
反应条件
sec.-butyllithium; (-)-sparteine 1.) Et2O, -78 deg C, 6 h, 2.) Et2O, from -78 deg C to RT, overnight; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Beak, Peter; Kerrick, Shawn T.; Wu, Shengde; Chu, Jingxi
Journal of the American Chemical Society, 1994 , vol. 116, # 8 p. 3231 - 3239