1.1: lithium hexamethyldisilazane / tetrahydrofuran / 1.5 h / -78 - -45 °C / Inert atmosphere 1.2: 3 h / -45 °C / Inert atmosphere 2.1: water; lithium hydroxide hydrate / tetrahydrofuran; methanol / 2 h / 20 - 55 °C / Inert atmosphere 3.1: 4-(N,N-dimethlyamino)pyridine; (2,6-Me(NO2)PhCO)2O; sodium hydrogencarbonate; triethylamine / dichloromethane; water / 12 h / 0 - 20 °C / Inert atmosphere 4.1: 10 palladium on activated charcoal; hydrogen / ethanol / 2 h / 20 °C / Inert atmosphere View Scheme

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 1.5 h / -78 - -45 °C / Inert atmosphere 1.2: 3 h / -45 °C / Inert atmosphere 2.1: water; lithium hydroxide hydrate / tetrahydrofuran; methanol / 2 h / 20 - 55 °C / Inert atmosphere 3.1: 4-(N,N-dimethlyamino)pyridine; (2,6-Me(NO2)PhCO)2O; sodium hydrogencarbonate; triethylamine / dichloromethane; water / 12 h / 0 - 20 °C / Inert atmosphere 4.1: 10 palladium on activated charcoal; hydrogen / ethanol / 2 h / 20 °C / Inert atmosphere 5.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran; toluene / 3 h / 0 - 20 °C / Inert atmosphere View Scheme

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 1.5 h / -78 - -45 °C / Inert atmosphere 1.2: 3 h / -45 °C / Inert atmosphere 2.1: water; lithium hydroxide hydrate / tetrahydrofuran; methanol / 2 h / 20 - 55 °C / Inert atmosphere 3.1: 4-(N,N-dimethlyamino)pyridine; (2,6-Me(NO2)PhCO)2O; sodium hydrogencarbonate; triethylamine / dichloromethane; water / 12 h / 0 - 20 °C / Inert atmosphere 4.1: 10 palladium on activated charcoal; hydrogen / ethanol / 2 h / 20 °C / Inert atmosphere View Scheme