pyridine; 0,2,4-dichlorophenyl-0-methylisopropylamidothiophosphate T=25°C; 1 h;

1: azobis(isobutyronitrile) / 18 h / 80 °C 2: 1) n-BuLi, 2) methanol / 1) hexane, ether, -78 deg C, 30 min, 2) -78 deg C 3: 92 percent / DMPA, pyridine / 1 h / 25 °C View Scheme

1: 1) n-BuLi, 2) methanol / 1) hexane, ether, -78 deg C, 30 min, 2) -78 deg C 2: 92 percent / DMPA, pyridine / 1 h / 25 °C View Scheme