1: 1) NaN(SiMe3)2 / 1) THF, 20 deg C, 15 min 2) THF, 20 deg C, 90 min 2: H2 / Pd/C / ethanol / 24 h / 20 °C / 2585.7 Torr 4: LiOH, H2O2 / tetrahydrofuran; H2O / 0.5 h / 0 °C 5: TFA / CH2Cl2 / 30 h / 20 °C 6: HOBT, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide*HCl / CH2Cl2 / 3 h / 0 to 20 deg c 7: H2 / Pd/C / ethyl acetate / 2 h / 20 °C 8: Et3N / tetrahydrofuran / 3 h / 0 °C 9: TBAF / tetrahydrofuran / 3 h / 0 °C 10: Et3N, DMAP / CH2Cl2 / 3 h / 20 °C 11: H2 / Pd/C / methanol; ethyl acetate 12: 66 percent / HOBT, 1-(3-dimethylaminopropyl)-ethylcarbodiimide*HCl / CH2Cl2; dimethylformamide / 10 h / 0 to 20 deg C 13: 54 percent / TBAF / tetrahydrofuran / 1.5 h / 20 °C View Scheme