反应条件
1: 2-bromobenzylmethyldiphenylphosphonium bromide With sodium hexamethyldisilazane in tetrahydrofuran
Wittig reaction; 1 h; Inert atmosphere;
2: benzaldehyde in tetrahydrofuran
T=-78 - 20°C; Wittig reaction; Inert atmosphereCooling with acetone-dry ice; optical yield given as percent dediastereoselective reaction;
参考文献
Byrne, Peter A.; Gilheany, Declan G.
Journal of the American Chemical Society, 2012 , vol. 134, # 22 p. 9225 - 9239