(5-碘-噻吩-2-基)-甲醇合成路线 （共 9 条）
反应条件
iodine; mercury(II) oxide in toluene 3 h;
参考文献
Muehlhausen, Ute; Schirrmacher, Ralf; Piel, Markus; Lecher, Bernd; Briegert, Manuela; Piee-Staffa, Andrea; Kaina, Bernd; Roesch, Frank
Journal of Medicinal Chemistry, 2006 , vol. 49, # 1 p. 263 - 272
反应条件
1: NaBH4 / methanol / 0.5 h / 0 °C 2: HgO, I2 / benzene / 1 h View Scheme
参考文献
D'Auria, M.; Mico, A. De; D'Onofrio, F.; Piancatelli, G.
Journal of Organic Chemistry, 1987 , vol. 52, # 23 p. 5243 - 5247
反应条件
1: PCC / CH2Cl2 2: 99 percent / acetonitrile / 3 h / Irradiation 3: 83 percent / benzyltriethylammonium chloride, CuI, Pd<P(Ph)3>4, 2.5Naq. NaOH / benzene / 3 h / 5 °C View Scheme
参考文献
D'Auria, M.; Mico, A. De; D'Onofrio, F.; Piancatelli, G.
Journal of Organic Chemistry, 1987 , vol. 52, # 23 p. 5243 - 5247
反应条件
1: PCC / CH2Cl2 2: 99 percent / acetonitrile / 3 h / Irradiation 3: 91 percent / NaBH4 / methanol; dioxane / 1 h / 0 °C 4: 95 percent / benzyltriethylammonium chloride, CuI, Pd<P(Ph)3>4, 2.5 N aq. NaOH / benzene / 3 h / 5 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 52, # 23 p. 5243 - 5247
反应条件
1: PCC / CH2Cl2 2: 99 percent / acetonitrile / 3 h / Irradiation View Scheme
参考文献
D'Auria, M.; Mico, A. De; D'Onofrio, F.; Piancatelli, G.
Journal of Organic Chemistry, 1987 , vol. 52, # 23 p. 5243 - 5247
反应条件
bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran T=60°C; 16 h;
参考文献
Crisp, Geoffrey T.
Synthetic Communications, 1989 , vol. 19, # 1, 2 p. 307 - 316
反应条件
1: PCC / CH2Cl2 2: 69 percent / acetonitrile / 3 h / Irradiation View Scheme
参考文献
D'Auria, M.; Mico, A. De; D'Onofrio, F.; Piancatelli, G.
Journal of Organic Chemistry, 1987 , vol. 52, # 23 p. 5243 - 5247
反应条件
1: PCC / CH2Cl2 2: 99 percent / acetonitrile / 3 h / Irradiation 3: 83 percent / benzyltriethylammonium chloride, CuI, Pd<P(Ph)3>4, 2.5Naq. NaOH / benzene / 3 h / 5 °C View Scheme
参考文献
D'Auria, M.; Mico, A. De; D'Onofrio, F.; Piancatelli, G.
Journal of Organic Chemistry, 1987 , vol. 52, # 23 p. 5243 - 5247
反应条件
pyridinium chlorochromate in dichloromethane
Inert atmosphereSchlenk technique;
参考文献
Mirloup, Antoine; Retailleau, Pascal; Ziessel, Raymond
Tetrahedron Letters, 2013 , vol. 54, # 33 p. 4456 - 4462
