反应条件
1: 1-methyl-pyrrolidin-2-one; ruthenium(III) chloride*(x)H2O; potassium carbonate; triphenylphosphine / 12 h / 140 °C / Inert atmosphere 2: methanol; sodium methylate / 9 h 3: trimethylsilyl bromide / acetonitrile / 4.5 h / 50 °C 4: N-ethyl-N,N-diisopropylamine / acetonitrile / 2 h / 50 °C 5: pyridine / toluene / 9 h / 20 - 40 °C 6: 5 Pd(II)/C(eggshell); ammonium formate / water / 4.23 h / 20 - 45 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 76, # 24 p. 10198 - 10206
