6-甲氧基-4-羟基喹啉合成路线 (共 13 条)
反应条件
in diphenylether 0.25 h; Heating;
参考文献
Cassis, Raul; Tapia, Ricardo; Valderrama, Jaime A.
Synthetic Communications, 1985 , vol. 15, # 2 p. 125 - 134
反应条件
palladium 10 on activated carbon; sodium hydroxide in water; isopropyl alcohol 16 h; Inert atmosphereReflux;
参考文献
Lange, Jens; Bissember, Alex C.; Banwell, Martin G.; Cade, Ian A.
Australian Journal of Chemistry, 2011 , vol. 64, # 4 p. 454 - 470
反应条件
1: dimethylformamide / 0.67 h / 100 °C 2: cyclohexane / Pd/C / ethanol / 1 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 5 p. 735 - 737
反应条件
1: dimethylformamide / 0.67 h / 100 °C 2: cyclohexane / Pd/C / ethanol / 1 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 46, # 5 p. 735 - 737
反应条件
1: With hydrogenchloride; sodium hydroxide in methanol T=2.5°C; Reflux; 2: T=250 - 260°C;
参考文献
European Journal of Medicinal Chemistry, , vol. 63, p. 907 - 923
反应条件
1: 51.3 percent / 0.25 h / 300 °C / 0.02 Torr View Scheme
参考文献
Synlett, , # 14 p. 2205 - 2208
反应条件
1: trifluorormethanesulfonic acid / dichloromethane / 1 h / 0 - 18 °C / Inert atmosphere 2: palladium 10 on activated carbon; sodium hydroxide / water; isopropyl alcohol / 16 h / Inert atmosphere; Reflux View Scheme
参考文献
Australian Journal of Chemistry, , vol. 64, # 4 p. 454 - 470
反应条件
1: copper(l) iodide; potassium carbonate / toluene / 20 h / 18 - 140 °C / Inert atmosphere; Sealed 2: trifluorormethanesulfonic acid / dichloromethane / 1 h / 0 - 18 °C / Inert atmosphere 3: palladium 10 on activated carbon; sodium hydroxide / water; isopropyl alcohol / 16 h / Inert atmosphere; Reflux View Scheme
参考文献
Australian Journal of Chemistry, , vol. 64, # 4 p. 454 - 470
反应条件
1.1: Dowtherm-A / ethanol / 250 - 260 °C 2.1: sodium hydroxide; hydrogenchloride / methanol / 2.5 °C / |Reflux 2.2: Dowtherm-A / 250 - 260 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 63, p. 907 - 923
反应条件
1: orthoformic acid triethyl ester; Polymer: 4-phenylbutan-2-one cyclic malonic acid ester, bound to Merrifield resin 6 h; Heating; 2: 4-methoxy-aniline 24 h; Heating; 3: T=220 - 240°C; 0.333333 h; Further stages.;
参考文献
Journal of Organic Chemistry, , vol. 67, # 19 p. 6731 - 6737