2,6-di-tert-butyl-4-methyl-phenol; lithium chloride; bis-triphenylphosphine-palladium(II) chloride; copper(I) bromide in N,N-dimethyl-formamide Heating;

1: 70 percent / 2,4,6-trimethylpyridine / CH2Cl2 2: 46 percent / 2,6-di-tert-butyl-4-methylphenol / PdCl2(PPh3)2, Ph3P, LiCl / dimethylformamide / 23 h / 145 °C View Scheme