2-异氰酰基-3-甲基丁酸乙酯合成路线 （共 8 条）
反应条件
1: in toluene T=0°C; 2: in toluene T=0 - 50°C; Further stages.;
参考文献
Lebedev; Lebedeva; Sheludyakov; Shatunov; Ovcharuk
Russian Journal of General Chemistry, 2007 , vol. 77, # 4 p. 581 - 585
反应条件
triethylamine in dichloromethane T=-10 - 0°C;
参考文献
Huang, Jun-Min; Chen, Hui; Chen, Ru-Yu
Synthetic Communications, 2002 , vol. 32, # 9 p. 1357 - 1363
反应条件
1: isopropylaminoacetic acid ethyl ester With hydrogenchloride 0.5 h; 2: phosgene T=20°C; 12 h;
参考文献
Wattanasin, Sompong; Weidmann, Beat; Roche, Didier; Myers, Stewart; Xing, Amy; Guo, Qin; Sabio, Michael; Von Matt, Peter; Hugo, Ronald; Maida, Susan; Lake, Philip; Weetall, Marla
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 22 p. 2955 - 2958
反应条件
1.1: 99.1 percent / Me3SiCl / Heating 2.1: toluene / 5 h / 90 - 95 °C 3.1: toluene / 0 °C 3.2: 80 percent / toluene / 0 - 50 °C View Scheme
参考文献
Lebedev; Lebedeva; Sheludyakov; Shatunov; Ovcharuk
Russian Journal of General Chemistry, 2007 , vol. 77, # 4 p. 581 - 585
反应条件
toluene T=130 - 160°C;
参考文献
Goldschmidt; Wick
Justus Liebigs Annalen der Chemie, 1952 , vol. 575, p. 217,230
参考文献
Baudet,P. et al.
Helvetica Chimica Acta, 1965 , vol. 48, p. 2005 - 2022
反应条件
1: Et2NH 2: CH2N2 View Scheme
参考文献
Baudet,P. et al.
Helvetica Chimica Acta, 1965 , vol. 48, p. 2005 - 2022
反应条件
1.1: toluene / 5 h / 90 - 95 °C 2.1: toluene / 0 °C 2.2: 80 percent / toluene / 0 - 50 °C View Scheme
参考文献
Lebedev; Lebedeva; Sheludyakov; Shatunov; Ovcharuk
Russian Journal of General Chemistry, 2007 , vol. 77, # 4 p. 581 - 585
