(2R)-(3-氟苯基)(羟基)乙腈合成路线 (共 3 条)
反应条件
citrate-phosphate buffer; Arabidopsis thaliana hydroxynitrile lyase in di-isopropyl ether
T=10°C; pH=5.0; 2 h;
参考文献
Andexer, Jennifer; Von Langermann, Jan; Mell, Annett; Bocola, Marco; Kragl, Udo; Eggert, Thorsten; Pohl, Martina
Angewandte Chemie - International Edition, 2007 , vol. 46, # 45 p. 8679 - 8681
反应条件
lipase PS-30 in diethyl ether
T=15°C; 27 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Xu, Qing; Geng, Xiaohong; Chen, Peiran
Tetrahedron Letters, 2008 , vol. 49, # 45 p. 6440 - 6441
反应条件
toluene-4-sulfonic acid in ethanol; water
T=20°C; 48 h;
参考文献
North, Michael; Omedes-Pujol, Marta; Williamson, Courtney
Chemistry - A European Journal, 2010 , vol. 16, # 37 p. 11367 - 11375