1: With n-butyllithium in tetrahydrofuran; hexane T=-90°C; Metallation; 0.25 h; 2: With boric acid trimethyl ester in tetrahydrofuran; hexane T=-90 - 20°C; boronation; 2 h; 3: With hydrogenchloride Hydrolysis; pH=5 - 6; cooling;

tripotassium phosphate monohydrate; 4-bromo-benzoic acid ethyl ester; C52H49PRu; bis(dibenzylideneacetone)-palladium(0) in 1,4-dioxane T=100°C; Suzuki-Miyaura Coupling; 4 h; Inert atmosphere;

tripotassium phosphate monohydrate; 4-bromo-benzoic acid ethyl ester; C52H49PRu; bis(dibenzylideneacetone)-palladium(0) in 1,4-dioxane T=100°C; Suzuki-Miyaura Coupling; 3.5 h; Inert atmosphere; Overall yield = 251.7 mg;