2-溴-N-[2-(7-甲氧基萘-1-基)乙基]乙酰胺合成路线 (共 2 条)
反应条件
1: 2-(7-methoxynaphthalen-1-yl)ethylamine hydrochloride With potassium carbonate in water; ethyl acetate T=20°C; Schotten-Baumann reaction; 2: 2-bromo acetyl bromide in water; ethyl acetate T=0 - 20°C; Schotten-Baumann reaction; 1 h;
参考文献
Ettaoussi, Mohamed; Sabaouni, Ahmed; Rami, Marouan; Boutin, Jean A.; Delagrange, Philippe; Renard, Pierre; Spedding, Michael; Caignard, Daniel-Henri; Berthelot, Pascal; Yous, Said
European Journal of Medicinal Chemistry, 2012 , vol. 49, p. 310 - 323
反应条件
potassium carbonate in chloroform; water 0.5 h; Ambient temperature;
参考文献
Depreux; Lesieur; Mansour; Morgan; Howell; Renard; Caignard; Pfeiffer; Delagrange; Guardiola; Yous; Demarque; Adam; Andrieux
Journal of Medicinal Chemistry, 1994 , vol. 37, # 20 p. 3231 - 3239