7-甲氧基-1-萘基乙腈合成路线 （共 30 条）
反应条件
trichlorophosphate in dichloromethane; N,N-dimethyl-formamide T=85°C; 2 h;
参考文献
ALEMBIC PHARMACEUTICALS LIMITED; JAYARAMAN, Venkat, Raman; PANCHASARA, Dineshkumar, Ramabhai; PATEL, Ilesh; PRAJAPATI, Bhavesh; PATEL, Ketan; PATWA, Mitul; SHAH, Ankit
Patent: WO2014/1939 A1, 2014 ;
Location in patent: Page/Page column 17 ;
反应条件
ethylene,methyl methacrylate; palladium on activated carbon in toluene Heating / reflux;
参考文献
Souvie, Jean-Claude; Gonzalez Blanco, Isaac; Thominot, Gilles; Chapuis, Genevieve; Horvath, Stephane; Damien, Gerard
Patent: US2005/182276 A1, 2005 ;
Location in patent: Page/Page column 6 ;
反应条件
chloranil in toluene T=80°C; 2.5 h;
参考文献
Les Laboratoires Servier; Zard, Samir; Sire, Béatrice; Boumediene, Mehdi
Patent: US2013/289307 A1, 2013 ;
Location in patent: Paragraph 0051; 0052; 0053 ;
反应条件
in water; dimethyl sulfoxide T=65°C; 3 h;
参考文献
LES LABORATOIRES SERVIER
Patent: US2010/137628 A1, 2010 ;
Location in patent: Page/Page column 2 ;
反应条件
potassium carbonate in acetone 3 h; Reflux;
参考文献
SYMED LABS LIMITED; MOHAN RAO, Dodda; ANNA REDDY, Ambati
Patent: WO2014/64706 A1, 2014 ;
Location in patent: Page/Page column 74-75 ;
反应条件
toluene-4-sulfonic acid in benzene 1 h; Heating;
参考文献
Chu; Li
Synthetic Communications, 2001 , vol. 31, # 4 p. 621 - 629
反应条件
1: 95 percent / n-BuLi / tetrahydrofuran; hexane / 1 h / -78 °C 2: 90.7 percent / DDQ / CH2Cl2 / 20 °C 3: 88.2 percent / TsOH*H2O / benzene / 1 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 31, # 4 p. 621 - 629
反应条件
1: SOCl2 / CHCl3 / 2 h / Heating 2: conc. aq. NH3 / diethyl ether / 0.5 h 3: 83 percent / Et3N, (CF3CO)2O / tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Archiv der Pharmazie, , vol. 326, # 2 p. 119 - 120
反应条件
in dimethyl sulfoxide T=140 - 145°C; 3 h;
参考文献
Chinea, Kimberly; Vera, William J.; Sanchez, Jennifer; Banerjee, Ajoy K.
Organic Preparations and Procedures International, 2013 , vol. 45, # 4 p. 328 - 331
反应条件
1: conc. aq. NH3 / diethyl ether / 0.5 h 2: 83 percent / Et3N, (CF3CO)2O / tetrahydrofuran / 1 h / Ambient temperature View Scheme
参考文献
Archiv der Pharmazie, , vol. 326, # 2 p. 119 - 120
