3-BOC氨基-5甲基己酸合成路线 （共 16 条）
反应条件
ruthenium trichloride; sodium periodate in tetrachloromethane; acetonitrile T=20°C;
参考文献
Fuller, Amelia A.; Chen, Bin; Minter, Aaron R.; Mapp, Anna K.
Journal of the American Chemical Society, 2005 , vol. 127, # 15 p. 5376 - 5383
反应条件
sodium periodate in methanol T=20°C;
参考文献
Palomo, Claudio; Oiarbide, Mikel; Halder, Rajkumar; Kelso, Michael; Gomez-Bengoa, Enrique; Garcia, Jesus M.
Journal of the American Chemical Society, 2004 , vol. 126, # 30 p. 9188 - 9189
反应条件
water; lithium hydroxide hydrate in methanol T=20°C; 18 h;
参考文献
Peddie, Victoria; Butcher, Raymond J.; Robinson, Ward T.; Wilce, Matthew C. J.; Traore, Daouda A. K.; Abell, Andrew D.
Chemistry - A European Journal, 2012 , vol. 18, # 21 p. 6655 - 6662
反应条件
1: H2 / Pd/C / ethyl acetate / 20 °C 2: aq. (NH4)2Ce(NO3)6 / acetonitrile / 16 h / 0 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 39, # 6 p. 1063 - 1066
反应条件
1: LiAlH4 / tetrahydrofuran 2: 68 percent / NaIO4; RuCl3 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 127, # 15 p. 5376 - 5383
反应条件
1.1: 2,2'-isopropylidene bis[(4S)-4-tert-butyl-2-oxazoline]; Cu(OTf)2 / CH2Cl2 / 0.5 h / 20 °C 1.2: 86.6 percent / CH2Cl2 / 22 h / 20 °C 2.1: 92 percent / aq. NaIO4 / methanol / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 30 p. 9188 - 9189
反应条件
1.1: 2,2'-isopropylidene bis[(4S)-4-tert-butyl-2-oxazoline]; Cu(OTf)2 / CH2Cl2 / 0.5 h / 20 °C 1.2: 86.6 percent / CH2Cl2 / 22 h / 20 °C 2.1: 92 percent / aq. NaIO4 / methanol / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 30 p. 9188 - 9189
反应条件
1.1: t-BuOCl / CH2Cl2 2.1: EtMgBr / CH2Cl2; propan-2-ol; diethyl ether / 0 °C 2.2: propan-2-ol; CH2Cl2; diethyl ether / 0 - 20 °C 3.1: LiAlH4 / tetrahydrofuran / 0 - 20 °C 4.1: aq. K2CO3 / tetrahydrofuran / 20 °C / pH 10 5.1: 68 percent / aq. NaIO4; RuCl3 / CCl4; acetonitrile / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 125, # 23 p. 6846 - 6847
反应条件
1.1: EtMgBr / CH2Cl2; propan-2-ol; diethyl ether / 0 °C 1.2: propan-2-ol; CH2Cl2; diethyl ether / 0 - 20 °C 2.1: LiAlH4 / tetrahydrofuran / 0 - 20 °C 3.1: aq. K2CO3 / tetrahydrofuran / 20 °C / pH 10 4.1: 68 percent / aq. NaIO4; RuCl3 / CCl4; acetonitrile / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 125, # 23 p. 6846 - 6847
反应条件
1: 90 percent / HCOONH4 / 10percent Pd-C / methanol / Ambient temperature 2: NaOH / dioxane; H2O / 4 h / Ambient temperature View Scheme
参考文献
Synthesis, , # 11 p. 1104 - 1108
