(1R)-1-(2-吡啶基)-3-丁烯-1-胺合成路线 （共 6 条）
反应条件
periodic acid; methylamine in methanol 1 h; Yield given;
参考文献
Alvaro, Giuseppe; Savoia, Diego
Tetrahedron Asymmetry, 1996 , vol. 7, # 7 p. 2083 - 2092
反应条件
1: 95 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 0 - 5 °C 2: 40percent aq. MeNH2, H5IO6 / methanol / 1 h View Scheme
参考文献
Alvaro, Giuseppe; Savoia, Diego
Tetrahedron Asymmetry, 1996 , vol. 7, # 7 p. 2083 - 2092
反应条件
hydroxylammonium acetate in ethanol 24 h; Heating; Yield given;
参考文献
Aiqiao, Mi; Xun, Xiao; Lanjun, Wu; Yaozhong, Jiang
Synthetic Communications, 1991 , vol. 21, # 21 p. 2207 - 2212
反应条件
1: 90 percent / BF3*Et3O / benzene / 2.5 h 2: 1.) n-BuLi / 1.) hexane, THF, -78 deg C, 3 h, 2.) hexane , THF, -78 deg C 3: NH2OH*HOAc / ethanol / 24 h / Heating View Scheme
参考文献
Aiqiao, Mi; Xun, Xiao; Lanjun, Wu; Yaozhong, Jiang
Synthetic Communications, 1991 , vol. 21, # 21 p. 2207 - 2212
反应条件
1: 1.) n-BuLi / 1.) hexane, THF, -78 deg C, 3 h, 2.) hexane , THF, -78 deg C 2: NH2OH*HOAc / ethanol / 24 h / Heating View Scheme
参考文献
Aiqiao, Mi; Xun, Xiao; Lanjun, Wu; Yaozhong, Jiang
Synthetic Communications, 1991 , vol. 21, # 21 p. 2207 - 2212
反应条件
1.1: dichloromethane / 1 h / |Reflux; |Inert atmosphere 2.1: indium / methanol / 6 h / 20 °C / |Inert atmosphere 3.1: lead(IV) tetraacetate / dichloromethane; methanol / 0.5 h / 0 °C / |Inert atmosphere 3.2: 0.5 h / 0 °C / |Inert atmosphere View Scheme
参考文献
Hajri, Majdi; Blondelle, Clement; Martinez, Agathe; Vasse, Jean-Luc; Szymoniak, Jan
Tetrahedron Letters, 2013 , vol. 54, # 8 p. 1029 - 1031
