4-(4-氨基苯氧基)-1-哌啶甲酸叔丁酯合成路线 （共 7 条）
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; 4 h;
参考文献
Sankyo Company, Limited
Patent: EP1375482 A1, 2004 ;
Location in patent: Page 159 ;
反应条件
palladium in methanol; hexane
参考文献
Sankyo Company, Limited
Patent: US6555556 B1, 2003 ;
US 6555556 B1
反应条件
1: NaH / tetrahydrofuran 2: H2 / 10 percent Pd/C / methanol / 760 Torr View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 3 p. 561 - 566
反应条件
1: NaH / tetrahydrofuran 2: H2 / 10 percent Pd/C / methanol / 760 Torr View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 3 p. 561 - 566
反应条件
1: 77 percent / Ph3P; DEAD / tetrahydrofuran / 21 h / 20 °C 2: 98 percent / H2 / 10 percent Pd/C / ethanol / 15 h / 20 °C View Scheme
参考文献
Bioorganic and medicinal chemistry, , vol. 10, # 5 p. 1509 - 1523
反应条件
1: sodium tetrahydroborate / methanol / 4 h / 0 - 20 °C 2: potassium tert-butylate / dimethyl sulfoxide / 2 h / 20 °C 3: palladium 10 on activated carbon; hydrogen / methanol View Scheme
反应条件
triphenylphosphine; diethylazodicarboxylate Mitsunobu reaction;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 9 p. 1307 - 1310
