(2S,4r)-4-[(甲基磺酰基)氧基]-1,2-吡咯烷二羧酸 2-甲基 1-[(4-硝基苯基)甲基]酯合成路线 （共 7 条）
反应条件
triethylamine in dichloromethane T=0°C; 1 h;
参考文献
Oh, Chang-Hyun; Lee, Seung Chan; Park, Sung-Jin; Lee, In-Kyu; Nam, Ki Hong; Lee, Ki-Soo; Chung, Bong-Young; Cho, Jung-Hyuck
Archiv der Pharmazie, 1999 , vol. 332, # 4 p. 111 - 114
反应条件
1: 99 percent / acetyl chloride / 8 h / Heating 2: 93 percent / triethylamine / CH2Cl2 / 2 h 3: 88 percent / triethylamine / CH2Cl2 / 3 h / 0 °C View Scheme
参考文献
Oh, Chang-Hyun; Lee, Seung Chan; Park, Sung-Jin; Lee, In-Kyu; Nam, Ki Hong; Lee, Ki-Soo; Chung, Bong-Young; Cho, Jung-Hyuck
Archiv der Pharmazie, 1999 , vol. 332, # 4 p. 111 - 114
反应条件
1: 93 percent / triethylamine / CH2Cl2 / 2 h 2: 88 percent / triethylamine / CH2Cl2 / 3 h / 0 °C View Scheme
参考文献
Oh, Chang-Hyun; Lee, Seung Chan; Park, Sung-Jin; Lee, In-Kyu; Nam, Ki Hong; Lee, Ki-Soo; Chung, Bong-Young; Cho, Jung-Hyuck
Archiv der Pharmazie, 1999 , vol. 332, # 4 p. 111 - 114
反应条件
1: H2SO4 / 3 h / Heating 2: 97.1 percent / NEt3 / CH2Cl2 / 1 h / 0 °C View Scheme
参考文献
Nishino, Yutaka; Komurasaki, Tadafumi; Yuasa, Tetsuya; Kakinuma, Makoto; Izumi, Kenji; Kobayashi, Makoto; Fujiie, Shinichiro; Gotoh, Teruhiro; Masui, Yoshiyuki; Hajima, Makoto; Takahira, Masayuki; Okuyama, Akira; Kataoka, Takahiro
Organic Process Research and Development, 2003 , vol. 7, # 5 p. 649 - 654
反应条件
1: 93 percent / triethylamine / CH2Cl2 / 2 h 2: 88 percent / triethylamine / CH2Cl2 / 3 h / 0 °C View Scheme
参考文献
Lee; Lim; Kang; Yoo; Kim; Shin
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 11 p. 1347 - 1351
反应条件
sodium borohydride in tetrahydrofuran; ethanol
参考文献
Shionogi Seiyaku Kabushiki Kaisha
Patent: US5317016 A1, 1994 ;
反应条件
sodium tetrahydroborate; lithium chloride in tetrahydrofuran; ethanol T=20°C; 4 h;
参考文献
Lee; Lim; Kang; Yoo; Kim; Shin
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 11 p. 1347 - 1351
