sodium hydroxide; sodium tetrahydroborate; nickel dichloride in ethanol 24 h; Heating;

1: 1.) potassium t-butoxide 2.) ammonium acetate, acetic acid / 1.) THF, room temp., 4 h 2.) reflux, 3 h 2: 60 percent / NiCl2*6H2O, NaBH4, 40percent aq. sodium hydroxide / ethanol / 24 h / Heating View Scheme

1: 1.) potassium t-butoxide 2.) ammonium acetate, acetic acid / 1.) THF, room temp., 4 h 2.) reflux, 3 h 2: 60 percent / NiCl2*6H2O, NaBH4, 40percent aq. sodium hydroxide / ethanol / 24 h / Heating View Scheme

ammonium acetate; acetic acid 4 h; Heating;

1: 1) KOtBu, 2) NH4OAc / 2) AcOH, heating 2: NiCl2, NaBH4 View Scheme