(2-叔丁氧基羰基氨基-6-氟苯基)-乙酸合成路线 （共 5 条）
反应条件
hydrogenchloride in ethanol 0.25 h; Heating; Yield given;
参考文献
Wyeth
Patent: US2008/51585 A1, 2008 ;
Location in patent: Page/Page column 19 ;
反应条件
1: in tetrahydrofuran; cyclohexane
T=-45 - 20°C;
2: With hydrogenchloride in tetrahydrofuran; cyclohexane; water
pH=2 - 3; 0.0833333 - 0.166667 h;
参考文献
Wyeth
Patent: US2008/51585 A1, 2008 ;
Location in patent: Page/Page column 19 ;
反应条件
1: tetrahydrofuran / Heating
2: 1) s-BuLi / 1) THF, cyclohexane, -40 to -20 deg C, 2) -40 deg C, 1 min
View Scheme
参考文献
Clark; Muchowski; Fisher; Flippin; Repke; Souchet
Synthesis, 1991 , # 10 p. 871 - 878
反应条件
1: tetrahydrofuran / Heating
2: 1) s-BuLi / 1) THF, cyclohexane, -40 to -20 deg C, 2) -40 deg C, 1 min
View Scheme
参考文献
Clark; Muchowski; Fisher; Flippin; Repke; Souchet
Synthesis, 1991 , # 10 p. 871 - 878
反应条件
sec.-butyllithium
1) THF, cyclohexane, -40 to -20 deg C, 2) -40 deg C, 1 min; Multistep reaction;
参考文献
Clark; Muchowski; Fisher; Flippin; Repke; Souchet
Synthesis, 1991 , # 10 p. 871 - 878
