2-甲氧基-2-甲基丙酸合成路线 （共 24 条）
反应条件
1: With potassium hydroxide in water T=0°C; 5.15 h; 2: With hydrogenchloride in water pH=0;
参考文献
BAYER PHARMACEUTICALS CORPORATION
Patent: WO2006/133006 A2, 2006 ;
Location in patent: Page/Page column 47-48 ;
反应条件
methyl-1-propene in trichloroethane, 1,1,1- T=-20°C; 24 h; Title compound not separated from byproducts;
参考文献
Adam, Waldemar; Blancafort, Lluis
Journal of the American Chemical Society, 1996 , vol. 118, # 20 p. 4778 - 4787
反应条件
potassium hydroxide in methanol; water
反应条件
in trichloroethane, 1,1,1- T=-20°C; 24 h;
参考文献
Adam, Waldemar; Blancafort, Lluis
Journal of the American Chemical Society, 1996 , vol. 118, # 20 p. 4778 - 4787
反应条件
in trichloroethane, 1,1,1- T=-20°C; 15 h;
参考文献
Journal of the American Chemical Society, , vol. 118, # 20 p. 4778 - 4787
反应条件
potassium hydroxide in methanol T=50°C;
参考文献
Canadian Journal of Chemistry, , vol. 58, p. 2784 - 2788
反应条件
hydrogenchloride; sodium nitrite
参考文献
Journal of the American Chemical Society, , vol. 46, p. 412
反应条件
potassium hydroxide; thiourea T=50°C;
参考文献
Canadian Journal of Chemistry, , vol. 58, p. 2784 - 2788
反应条件
potassium hydroxide in ethanol; water Heating; Yield given;
参考文献
Tetrahedron, , vol. 53, # 42 p. 14287 - 14296
反应条件
sodium hydroxide in methanol 5 h; Ambient temperature;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 31, # 5 p. 1505 - 1517
