1.1: potassium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / water; tetrahydrofuran / 32 h / 20 - 45 °C / Inert atmosphere 2.1: hydrogen / 5 palladium on charcoal / methanol / 20 °C / 1551.49 Torr / Inert atmosphere 3.1: N,N-dimethyl-formamide; thionyl chloride / 5 h / 10 - 20 °C 4.1: sodium hexamethyldisilazane / N,N-dimethyl-formamide / 1 h / -15 °C 4.2: -10 - 12 °C View Scheme

hydrogen; 5 palladium on charcoal in methanol T=20°C; P=1292.9 Torr; 0.5 h; Inert atmosphere;

1: potassium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / water; tetrahydrofuran / 32 h / 20 - 45 °C / Inert atmosphere 2: hydrogen / 5 palladium on charcoal / methanol / 20 °C / 1551.49 Torr / Inert atmosphere View Scheme