甲基 4-((4-(叔丁氧基羰基)哌嗪)磺酰基)苯甲酸合成路线 （共 6 条）
反应条件
triethylamine; carbon monoxide in N-methyl-acetamide; methanol; ethyl acetate
参考文献
Ajinomoto Co., Inc.
Patent: EP976722 A1, 2000 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide 0.333333 h;
参考文献
Varney, Michael D.; Marzoni, Gifford P.; Palmer, Cindy L.; Deal, Judith G.; Webber, Stephanie; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 663 - 676
反应条件
1: 53 percent / DIEA / tetrahydrofuran / 1 h 2: 91 percent / K2CO3 / dimethylformamide / 0.33 h View Scheme
参考文献
Varney, Michael D.; Marzoni, Gifford P.; Palmer, Cindy L.; Deal, Judith G.; Webber, Stephanie; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 663 - 676
反应条件
1: 53 percent / DIEA / tetrahydrofuran / 1 h 2: 91 percent / K2CO3 / dimethylformamide / 0.33 h View Scheme
参考文献
Varney, Michael D.; Marzoni, Gifford P.; Palmer, Cindy L.; Deal, Judith G.; Webber, Stephanie; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 663 - 676
反应条件
1: 93 percent / 1 M DIBAL / tetrahydrofuran; hexane / 0.5 h 2: 96 percent / Ph3P, CBr4 / CH2Cl2 / 0.33 h 3: 47 percent / K2CO3 / dimethylformamide / 100 °C 4: 94 percent / HCl / methanol / Ambient temperature View Scheme
参考文献
Varney, Michael D.; Marzoni, Gifford P.; Palmer, Cindy L.; Deal, Judith G.; Webber, Stephanie; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 663 - 676
反应条件
hydrogenchloride; sodium hydroxide in tetrahydrofuran; methanol; ethyl acetate
参考文献
Ajinomoto Co., Inc.
Patent: EP976722 A1, 2000 ;
