1: With sodium hydroxide; tetrabutylammomium bromide in water; toluene T=85°C; 2 h; 2: With hydrogenchloride; water in acetone T=20°C; 3: With potassium hydroxide in water; acetone Product distribution / selectivity;
参考文献
CIPLA LIMITED; WAIN, Christopher, Paul
Patent: WO2006/46043 A1, 2006 ;
Location in patent: Page/Page column 23 ;
1: With sodium azide; tributyltin chloride; N,N-dimethyl-formamide in o-xylene T=15 - 155°C; 1 h; 2: With hydrogenchloride in dichloromethane; o-xylene; water T=20°C; 1 h; Product distribution / selectivity;
1: With sodium azide; tributyltin chloride; N,N-dimethyl-formamide in o-xylene T=15 - 155°C; 1 h; 2: With hydrogenchloride in dichloromethane; o-xylene; water T=20 - 25°C; 1.5 h; Product distribution / selectivity;
1: SR48001A With potassium carbonate; tetrabutylammomium bromide in water T=25 - 60°C; 2: 2-[4-(bromomethyl)phenyl]benzonitrile in water T=55 - 60°C; 3: With sodium azide; triethyl amine hydrochloride in toluene T=25 - 105°C; Product distribution / selectivity;
