9H-吡啶并[3,4-b]吲哚-1-乙酸甲酯合成路线 （共 10 条）
反应条件
palladium on activated charcoal in various solvent(s) T=160 - 170°C; 0.166667 h;
参考文献
Torisawa; Hashimoto; Nakagawa; Seki; Hara; Hino
Tetrahedron, 1991 , vol. 47, # 38 p. 8067 - 8078
反应条件
1: harmane With lithium diisopropyl amide in tetrahydrofuran T=-78°C; 0.25 h; 2: carbonic acid dimethyl ester in tetrahydrofuran T=-78°C; 0.833333 h;
参考文献
MaGee; Beck
Canadian Journal of Chemistry, 2000 , vol. 78, # 8 p. 1060 - 1066
反应条件
1: 76 percent / aq. NaOH / CH2Cl2 / 1 h / Ambient temperature 2: POCl3 / 12 h / Ambient temperature 3: 67 percent / 10percent Pd-C / various solvent(s) / 0.17 h / 160 - 170 °C View Scheme
参考文献
Torisawa; Hashimoto; Nakagawa; Seki; Hara; Hino
Tetrahedron, 1991 , vol. 47, # 38 p. 8067 - 8078
反应条件
1: POCl3 / 12 h / Ambient temperature 2: 67 percent / 10percent Pd-C / various solvent(s) / 0.17 h / 160 - 170 °C View Scheme
参考文献
Torisawa; Hashimoto; Nakagawa; Seki; Hara; Hino
Tetrahedron, 1991 , vol. 47, # 38 p. 8067 - 8078
反应条件
1: 89 percent / benzene / 17 h / Heating 2: 90 percent / 10percent Pd/C / 1,3,5-trimethyl-benzene / 4.5 h / Heating 3: 1) 0.2 N H2SO4, dioxane, 2) 2 N KOH / 1) reflux, 4 h, 2) reflux, 4 h View Scheme
参考文献
Nowak, Wolfgang; Gerlach, Hans
Liebigs Annalen der Chemie, 1993 , # 2 p. 153 - 160
反应条件
1: 100 percent / LiAlH4 / tetrahydrofuran / 4.5 h / Heating 2: 89 percent / benzene / 17 h / Heating 3: 90 percent / 10percent Pd/C / 1,3,5-trimethyl-benzene / 4.5 h / Heating 4: 1) 0.2 N H2SO4, dioxane, 2) 2 N KOH / 1) reflux, 4 h, 2) reflux, 4 h View Scheme
参考文献
Nowak, Wolfgang; Gerlach, Hans
Liebigs Annalen der Chemie, 1993 , # 2 p. 153 - 160
反应条件
1: 90 percent / 10percent Pd/C / 1,3,5-trimethyl-benzene / 4.5 h / Heating 2: 1) 0.2 N H2SO4, dioxane, 2) 2 N KOH / 1) reflux, 4 h, 2) reflux, 4 h View Scheme
参考文献
Nowak, Wolfgang; Gerlach, Hans
Liebigs Annalen der Chemie, 1993 , # 2 p. 153 - 160
反应条件
potassium dichromate; acetic acid 0.05 h; Heating;
参考文献
Song, Yongcheng; Wang, Jian; Teng, Su Fern; Kesuma, Djohan; Deng, Yu; Duan, Jinao; Wang, Jerry H.; Qi, Robert Zhong; Sim, Mui Mui
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 7 p. 1129 - 1132
反应条件
1: aq. H2SO4 / 12 h / 65 °C 2: K2Cr2O7; aq. AcOH / 0.05 h / Heating 3: K2Cr2O7; aq. AcOH / 0.05 h / Heating View Scheme
参考文献
Song, Yongcheng; Wang, Jian; Teng, Su Fern; Kesuma, Djohan; Deng, Yu; Duan, Jinao; Wang, Jerry H.; Qi, Robert Zhong; Sim, Mui Mui
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 7 p. 1129 - 1132
反应条件
1,4-dioxane; potassium hydroxide; sulfuric acid 1) reflux, 4 h, 2) reflux, 4 h; Yield given. Multistep reaction;
参考文献
Nowak, Wolfgang; Gerlach, Hans
Liebigs Annalen der Chemie, 1993 , # 2 p. 153 - 160
