sodium acetate; bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl acetamide T=130°C;

1: 1.) oxalyl chloride, DMF, 2.) Et3N, DMAP / 1.) CH2Cl2, 0 deg, 1 h -> r. t., 3 h, 2.) CHCl2, r. t., 3 h 2: 72 percent / NaOAc / bis(triphenylphosphane)palladium dichloride / N,N-dimethyl-acetamide / 130 °C View Scheme

1: 1.) oxalyl chloride, DMF, 2.) Et3N, DMAP / 1.) CH2Cl2, 0 deg, 1 h -> r. t., 3 h, 2.) CHCl2, r. t., 3 h 2: 72 percent / NaOAc / bis(triphenylphosphane)palladium dichloride / N,N-dimethyl-acetamide / 130 °C View Scheme