反应条件
1: 14.06 g / LiAlH4 / diethyl ether / a.) 0 deg C, 10 min, b.) room temperature, 3.5 h
2: 83 percent / Et3N, DMAP / CH2Cl2 / 20 h / Ambient temperature
3: 91 percent / H2 / 10percent Pd-C / ethanol / Ambient temperature
4: H2O; propan-2-ol / pig pancreatic lipase, pH 7 buffer (K2HPO4-KH2PO4)
View Scheme
参考文献
Guanti, Giuseppe; Banfi, Luca; Narisano, Enrica
Journal of Organic Chemistry, 1992 , vol. 57, # 5 p. 1540 - 1554