(3beta)-3-[[(1,1-二甲基乙基)二甲基硅烷基]氧基]-26,27-二去甲胆甾-5-烯-25-腈合成路线 （共 2 条）
反应条件
Multi-step reaction with 3 steps 1: 1H-imidazole; carbon tetrabromide; triphenylphosphine / diethyl ether; acetonitrile / 0 - 20 °C / Inert atmosphere2: acetone / 23 h / 20 °C / Inert atmosphere3: N,N-dimethyl-formamide / 2 h / 80 °C / Inert atmosphere
参考文献
Johnston, Jonathan B.; Singh, Arti A.; Clary, Anaelle A.; Chen, Chiung-Kuan; Hayes, Patricia Y.; Chow, Sharon; De Voss, James J.; Ortiz De Montellano, Paul R. Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 13 p. 4064 - 4081
反应条件
Multi-step reaction with 2 steps 1: acetone / 23 h / 20 °C / Inert atmosphere2: N,N-dimethyl-formamide / 2 h / 80 °C / Inert atmosphere
参考文献
Johnston, Jonathan B.; Singh, Arti A.; Clary, Anaelle A.; Chen, Chiung-Kuan; Hayes, Patricia Y.; Chow, Sharon; De Voss, James J.; Ortiz De Montellano, Paul R. Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 13 p. 4064 - 4081
