2-(4-氟苯基)-丙酸-1,3-二乙酯合成路线 （共 3 条）
反应条件
sodium methylate in methanol T=60°C; 1 h;
参考文献
Dannhardt, G; Meindl, W; Schober, B D; Kappe, T
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 6 p. 599 - 604
反应条件
sodium hydride in tetrahydrofuran; paraffin 2 h; Heating;
参考文献
Shintani, Ryo; Ito, Tomoaki; Nagamoto, Midori; Otomo, Haruka; Hayashi, Tamio
Chemical Communications, 2012 , vol. 48, # 79 p. 9936 - 9938
反应条件
1: thionyl chloride / 6 h / 0 - 20 °C 2: sodium hydride / mineral oil / 12 h / 0 - 20 °C View Scheme
参考文献
Shintani, Ryo; Ito, Tomoaki; Nagamoto, Midori; Otomo, Haruka; Hayashi, Tamio
Chemical Communications, 2012 , vol. 48, # 79 p. 9936 - 9938
