双吲哚马来酰亚胺 IX 甲烷磺酸盐合成路线 （共 6 条）
反应条件
in ethanol 18 h; Heating;
参考文献
Davis, Peter D.; Elliot, Lucy H.; Harris, William; Hill, Christopher H.; Hurst, Steven A.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 6 p. 994 - 1001
反应条件
1: 1.) NaH / 1.) DMF, 0.5 h, 2.) DMF, RT, 18 h 2: CH2Cl2 / 3 h / Ambient temperature 3: Et3N / CH2Cl2 / 18 h / Ambient temperature 4: 94 percent / 33percent aq. ammonia / dimethylformamide / 4 h / 140 °C 5: 73 percent / pyridine / CH2Cl2 / 20 h / Ambient temperature 6: 79 percent / ethanol / 18 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 6 p. 994 - 1001
反应条件
1: CH2Cl2 / 3 h / Ambient temperature 2: Et3N / CH2Cl2 / 18 h / Ambient temperature 3: 94 percent / 33percent aq. ammonia / dimethylformamide / 4 h / 140 °C 4: 73 percent / pyridine / CH2Cl2 / 20 h / Ambient temperature 5: 79 percent / ethanol / 18 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 6 p. 994 - 1001
反应条件
1: 73 percent / pyridine / CH2Cl2 / 20 h / Ambient temperature 2: 79 percent / ethanol / 18 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 6 p. 994 - 1001
反应条件
1: 94 percent / 33percent aq. ammonia / dimethylformamide / 4 h / 140 °C 2: 73 percent / pyridine / CH2Cl2 / 20 h / Ambient temperature 3: 79 percent / ethanol / 18 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 6 p. 994 - 1001
