(3,4-二甲氧基-2-(三氟甲基)苯基)甲醇合成路线 （共 4 条）
反应条件
sodium tetrahydroborate in tetrahydrofuran; water T=40°C; 2.5 h;
参考文献
Markovich; Tantishaiyakul; Hamada; Miller; Romstedt; Shams; Shin; Fraundorfer; Doyle; Feller
Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 466 - 479
反应条件
1: 73 percent / pyridine, iodine monochloride / dioxane / 144 h / Ambient temperature 2: 85 percent / potassium carbonate / acetone / 6 h / Heating 3: 40 percent / cuprous iodide / various solvent(s) / 4 h / 175 °C 4: 87 percent / sodium borohydride / tetrahydrofuran; H2O / 2.5 h / 40 °C View Scheme
参考文献
Markovich; Tantishaiyakul; Hamada; Miller; Romstedt; Shams; Shin; Fraundorfer; Doyle; Feller
Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 466 - 479
反应条件
1: 40 percent / cuprous iodide / various solvent(s) / 4 h / 175 °C 2: 87 percent / sodium borohydride / tetrahydrofuran; H2O / 2.5 h / 40 °C View Scheme
参考文献
Markovich; Tantishaiyakul; Hamada; Miller; Romstedt; Shams; Shin; Fraundorfer; Doyle; Feller
Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 466 - 479
反应条件
1: 85 percent / potassium carbonate / acetone / 6 h / Heating 2: 40 percent / cuprous iodide / various solvent(s) / 4 h / 175 °C 3: 87 percent / sodium borohydride / tetrahydrofuran; H2O / 2.5 h / 40 °C View Scheme
参考文献
Markovich; Tantishaiyakul; Hamada; Miller; Romstedt; Shams; Shin; Fraundorfer; Doyle; Feller
Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 466 - 479
