4-溴甲基苯硼酸频哪醇酯合成路线 （共 29 条）
反应条件
carbon tetrabromide; triphenylphosphine in tetrahydrofuran T=20°C; 4 h; Cooling with ice;
参考文献
PROMEGA CORPORATION; KLAUBERT, Dieter; SHULTZ, John; UNCH, James; VALLEY, Michael P.; WANG, Hui; ZHOU, Wenhui
Patent: WO2013/25885 A1, 2013 ;
Location in patent: Paragraph 0086 ;
反应条件
N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in cyclohexane 5 h; Heating;
参考文献
RATIOPHARM GMBH
Patent: WO2006/81807 A2, 2006 ;
Location in patent: Page/Page column 20; 32 ;
反应条件
in hexane T=20°C; Condensation; 24 h;
参考文献
Ramalingam, Kondareddiar; Nowotnik, David P.
Organic Preparations and Procedures International, 1991 , vol. 23, # 6 p. 729 - 734
反应条件
1: tetrahydrofuran; diethyl ether / 20 h / 60 °C / |Inert atmosphere; |Schlenk technique 2: 2,2'-azo-bisisobutyronitrile; N-bromosuccinmide / tetrachloromethane / 3 h / |Inert atmosphere; |Schlenk technique; |Reflux; |Irradiation View Scheme
参考文献
Organic Letters, , vol. 15, # 4 p. 917 - 919
反应条件
1: sulfuric acid / tetrahydrofuran; diethyl ether; water / 0.17 h / 20 °C / |Inert atmosphere; |Schlenk technique 2: tetrahydrofuran; diethyl ether / 20 h / 60 °C / |Inert atmosphere; |Schlenk technique 3: 2,2'-azo-bisisobutyronitrile; N-bromosuccinmide / tetrachloromethane / 3 h / |Inert atmosphere; |Schlenk technique; |Reflux; |Irradiation View Scheme
参考文献
Organic Letters, , vol. 15, # 4 p. 917 - 919
反应条件
1.1: magnesium / tetrahydrofuran / 1 h / |Inert atmosphere; |Schlenk technique; |Reflux 1.2: 4.33 h / -95 - 20 °C / |Inert atmosphere; |Schlenk technique 2.1: sulfuric acid / tetrahydrofuran; diethyl ether; water / 0.17 h / 20 °C / |Inert atmosphere; |Schlenk technique 3.1: tetrahydrofuran; diethyl ether / 20 h / 60 °C / |Inert atmosphere; |Schlenk technique 4.1: 2,2'-azo-bisisobutyronitrile; N-bromosuccinmide / tetrachloromethane / 3 h / |Inert atmosphere; |Schlenk technique; |Reflux; |Irradiation View Scheme
参考文献
Organic Letters, , vol. 15, # 4 p. 917 - 919
反应条件
1: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / dimethyl sulfoxide / 18 h / 85 °C / Inert atmosphere 2: triethylamine / dichloromethane / 2 h / 0 °C / Inert atmosphere 3: potassium bromide / N,N-dimethyl-formamide / 19 h / 20 °C / Inert atmosphere View Scheme
反应条件
1: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / dimethyl sulfoxide / 18 h / 85 °C / Inert atmosphere 2: triethylamine / dichloromethane / 2 h / 0 °C / Inert atmosphere 3: potassium bromide / N,N-dimethyl-formamide / 19 h / 20 °C / Inert atmosphere View Scheme
反应条件
1: 84 percent / cyclohexane / 10 h / Heating 2: 86 percent / NBS; AIBN / cyclohexane / 5 h / Heating View Scheme
参考文献
Synlett, , # 3 p. 475 - 477
反应条件
1: 84 percent / cyclohexane / 10 h / Heating 2: 86 percent / NBS; AIBN / cyclohexane / 5 h / Heating View Scheme
参考文献
Synlett, , # 3 p. 475 - 477
