6-氯-2-甲基-咪唑并[1,2-A]吡啶-3-羧酸合成路线 (共 2 条)
反应条件
1: ethylene glycol dimethyl ether / 48 h / |Reflux; |Inert atmosphere 2: lithium hydroxide hydrate / ethanol / |Inert atmosphere View Scheme
参考文献
Moraski, Garrett C.; Markley, Lowell D.; Cramer, Jeffrey; Hipskind, Philip A.; Boshoff, Helena; Bailey, Mai A.; Alling, Torey; Ollinger, Juliane; Parish, Tanya; Miller, Marvin J.
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 7 p. 675 - 679
反应条件
lithium hydroxide hydrate in ethanol Inert atmosphere;
参考文献
Moraski, Garrett C.; Markley, Lowell D.; Cramer, Jeffrey; Hipskind, Philip A.; Boshoff, Helena; Bailey, Mai A.; Alling, Torey; Ollinger, Juliane; Parish, Tanya; Miller, Marvin J.
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 7 p. 675 - 679