3,6-二氢-4-[[(三氟甲基)磺酰]氧基]-1(2H)-吡啶甲酸叔丁酯合成路线

138647-49-13,6-二氢-4-[[(三氟甲基)磺酰]氧基]-1(2H)-吡啶甲酸叔丁酯

参考文献

JANSSEN RandD IRELAND; GUILLEMONT, Jerôme Emile Georges; LANÇOIS, David Francis Alain; MOTTE, Magali Madeleine Simone; BALEMANS, Wendy Mia Albert; KOUL, Anil
Patent: WO2014/23815 A1, 2014 ;

138647-49-13,6-二氢-4-[[(三氟甲基)磺酰]氧基]-1(2H)-吡啶甲酸叔丁酯

10338-69-94-苯基-1,2,3,6-四氢吡啶

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 22 p. 3951 - 3954

138647-49-13,6-二氢-4-[[(三氟甲基)磺酰]氧基]-1(2H)-吡啶甲酸叔丁酯

37656-48-74-(4-氟苯基)呱碇

参考文献

SK Chemicals Co.,Ltd.; RYU, Je Ho; KIM, Shin Ae; RYU, Keun Ho; KIM, Jae Sun; KIM, Nam Ho; HAN, Hye Young; KIM, Yong Hyuk; YOUN, Won-No; LEE, Yoon-Jung; SON, Hyun Joo; LEE, Bong-yong; PARK, Sung Hoon; LEE, Ju Young; LEE, Hyun Jung; JUNG, Hoe Chul; SHIN, Young Ah; LEE, Jung A; LEE, Bo Ram; SA, Joon Ho
Patent: WO2011/139107 A2, 2011 ;
WO 2011/139107 A2

138647-49-13,6-二氢-4-[[(三氟甲基)磺酰]氧基]-1(2H)-吡啶甲酸叔丁酯

143924-45-22-(哌啶-4-基)吡啶双盐酸盐

参考文献

Patel, Meena V.; Kolasa, Teodozyj; Mortell, Kathleen; Matulenko, Mark A.; Hakeem, Ahmed A.; Rohde, Jeffrey J.; Nelson, Sherry L.; Cowart, Marlon D.; Nakane, Masaki; Miller, Loan N.; Uchic, Marie E.; Terranova, Marc A.; El-Kouhen, Odile F.; Donnelly-Roberts, Diana L.; Namovic, Marian T.; Hollingsworth, Peter R.; Chang, Renjie; Martino, Brenda R.; Wetter, Jill M.; Marsh, Kennan C.; Martin, Ruth; Darbyshire, John F.; Gintant, Gary; Hsieh, Gin C.; Moreland, Robert B.; Sullivan, James P.; Brioni, Jorge D.; Stewart, Andrew O.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7450 - 7465

138647-49-13,6-二氢-4-[[(三氟甲基)磺酰]氧基]-1(2H)-吡啶甲酸叔丁酯

30532-37-72-(4-哌啶基)吡啶

参考文献

Cowart, Marlon; Latshaw, Steven P.; Bhatia, Pramila; Daanen, Jerome F.; Rohde, Jeffrey; Nelson, Sherry L.; Patel, Meena; Kolasa, Teodozyi; Nakane, Masaki; Uchic, Marie E.; Miller, Loan N.; Terranova, Marc A.; Chang, Renjie; Donnelly-Roberts, Diana L.; Namovic, Marian T.; Hollingsworth, Peter R.; Martino, Brenda R.; Lynch III, James J.; Sullivan, James P.; Hsieh, Gin C.; Moreland, Robert B.; Brioni, Jorge D.; Stewart, Andrew O.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 15 p. 3853 - 3864

138647-49-13,6-二氢-4-[[(三氟甲基)磺酰]氧基]-1(2H)-吡啶甲酸叔丁酯

170011-57-14-(4-氨基苯基)哌啶-1-甲酸叔丁酯

参考文献

AFRAXIS, INC.; CAMPBELL, David; DURÓN, Sergio, G.
Patent: WO2013/43232 A2, 2013 ;
WO 2013/043232 A2

168824-94-0叔丁基-3,4-二氢- 1H-吡啶[3,4 - b]吲哚-2（9H）-羧酸

参考文献

Jana, Navendu; Nguyen, Quyen; Driver, Tom G.
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2781 - 2791

138647-49-13,6-二氢-4-[[(三氟甲基)磺酰]氧基]-1(2H)-吡啶甲酸叔丁酯

1978-59-24-(4-氟苯基)-1,2,3,6-四氢吡啶

参考文献

Chen, Jian Jeffrey; Dewdney, Nolan; Lin, Xiaohong; Martin, Robert L.; Walker, Keith A. M.; Huang, Jane; Chu, Frances; Eugui, Elsie; Mirkovich, Anna; Kim, Yong; Sarma, Keshab; Arzeno, Humberto; Van Wart, Harold E.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 22 p. 3951 - 3954

138647-49-13,6-二氢-4-[[(三氟甲基)磺酰]氧基]-1(2H)-吡啶甲酸叔丁酯

186347-72-84-苯基-3,6-二氢-2H-吡啶-1-羧酸叔丁酯

参考文献

Scheiper, Bodo; Bonnekessel, Melanie; Krause, Helga; Fuerstner, Alois
Journal of Organic Chemistry, 2004 , vol. 69, # 11 p. 3943 - 3949

138647-49-13,6-二氢-4-[[(三氟甲基)磺酰]氧基]-1(2H)-吡啶甲酸叔丁酯+

98-80-6苯硼酸

186347-72-84-苯基-3,6-二氢-2H-吡啶-1-羧酸叔丁酯

参考文献

Chen, Jian Jeffrey; Dewdney, Nolan; Lin, Xiaohong; Martin, Robert L.; Walker, Keith A. M.; Huang, Jane; Chu, Frances; Eugui, Elsie; Mirkovich, Anna; Kim, Yong; Sarma, Keshab; Arzeno, Humberto; Van Wart, Harold E.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 22 p. 3951 - 3954