2,2-二甲基-3-氧代丙酸甲酯合成路线 （共 10 条）
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane T=-78 - 20°C; Oxidation; Swern oxidation;
参考文献
Mukaiyama, Teruaki; Shiina, Isamu; Iwadare, Hayato; Saitoh, Masahiro; Nishimura, Toshihiro; Ohkawa, Naoto; Sakoh, Hiroki; Nishimura, Koji; Tani, Yu-Ichirou; Hasegawa, Masatoshi; Yamada, Koji; Saitoh, Katsuyuki
Chemistry - A European Journal, 1999 , vol. 5, # 1 p. 121 - 161
反应条件
hydrogen; (η6-C6H5BPh3)(1-)*Rh(1+)*(1,5-COD); 1,4-di(diphenylphosphino)-butane in dichloromethane T=100°C; P=31028.9 Torr; 18 h; Yields of byproduct given;
参考文献
Lee, Chul Woo; Alper, Howard
Journal of Organic Chemistry, 1995 , vol. 60, # 3 p. 499 - 503
反应条件
hydrogen; [rhodium(I)(carbonyl)2(acetylacetonate)]; (Me)CgPPh in toluene T=50°C; P=37503 Torr; 24 h;
参考文献
Clarke, Matthew L.; Roff, Geoffrey J.
Chemistry - A European Journal, 2006 , vol. 12, # 31 p. 7979 - 7986
反应条件
triethylamine in hexane; dichloromethane; dimethyl sulfoxide
参考文献
Pharmacia and Upjohn Company
Patent: US5877317 A1, 1999 ;
反应条件
hydrogen; RhH(CO)(triphenylphosphine)3 in benzene T=80°C; P=5171.5 Torr; 5 h; other P/Ph ratios, other pressures, other <H2>/<CO> ratios, other temperatures, other solvents, other catalysts; Product distribution;
参考文献
Alper, Howard; Zhou, Jian-Qiang
Journal of Organic Chemistry, 1992 , vol. 57, # 13 p. 3729 - 3731
反应条件
hydrogen; dodecacarbonyltetrarhodium(0) in toluene T=120°C; P=83600.1 Torr; 78 h; other methacrylic derivatives; other catalysts; var. solvents, var. times, temp. and pressures; Product distributionMechanism;
参考文献
Koeken, Ard C. J.; Smeets, Niels M. B.
Catalysis Science and Technology, 2013 , vol. 3, # 4 p. 1036 - 1045
反应条件
hydrogen; (η6-C6H5BPh3)(1-)*Rh(1+)*(1,5-COD) in dichloromethane T=100°C; P=31028.9 Torr; 18 h; various temp., time and catalysts; Product distribution;
参考文献
Lee, Chul Woo; Alper, Howard
Journal of Organic Chemistry, 1995 , vol. 60, # 3 p. 499 - 503
反应条件
water; zinc(II) chloride in dichloromethane T=20 - 25°C; Yield given. Yields of byproduct given;
参考文献
Tanimoto, Shigeo; Kokubo, Toshio; Oida, Tatsuo; Ikehira, Hideyuki
Synthesis, 1982 , # 9 p. 723 - 725
反应条件
1: 98 percent Spectr. / trimethylsilyl trifluoromethanesulphonate / acetonitrile / 3 h / 25 - 30 °C 2: 95percent aq. MeOH, Cu(OAc)2 / 0.5 h / Heating View Scheme
参考文献
Okano, Kohji; Morimoto, Toshiaki; Sekiya, Minoru
Journal of the Chemical Society, Chemical Communications, 1985 , # 3 p. 119 - 120
参考文献
Chen,F.; Ainsworth,C.
Journal of the American Chemical Society, 1972 , vol. 94, p. 4037 - 4038
