1: With pyridine; palladium diacetate; tetrabutyl-ammonium chloride in N,N-dimethyl-formamide T=100°C; P=760 Torr; 12 h; 2: With sodium hydroxide in ethanol T=20°C; 0.5 h;

1.1: 95 percent / K2CO3 / acetone / 3 h / 20 °C 2.1: pyridine; n-Bu4NCl; Pd(OAc)2 / dimethylformamide / 12 h / 100 °C / 760 Torr 2.2: NaOH / ethanol / 0.5 h / 20 °C View Scheme