(R)-3-氨基-1-苯基-1-丙醇合成路线 （共 15 条）
反应条件
1: LAH / tetrahydrofuran / 1 h / 0 °C
2: Et3N / CH2Cl2 / 3 h / 20 °C
3: ethanol; H2O / 12 h / 20 °C
4: BH3*Me2S / tetrahydrofuran / 3 h / 65 °C
View Scheme
参考文献
Ghorai, Manas K.; Das, Kalpataru; Shukla, Dipti
Journal of Organic Chemistry, 2007 , vol. 72, # 15 p. 5859 - 5862
反应条件
water; triphenylphosphine in tetrahydrofuran
参考文献
Lowe 3rd., John A; Drozda, Susan E; Fisher, Katherine; Strick, Christine; Lebel, Lorraine; Schmidt, Christopher; Hiller, Donna; Zandi, Kathleen S
Bioorganic and medicinal chemistry letters, 2003 , vol. 13, # 7 p. 1291 - 1292
反应条件
1: NaI
2: NaN3
3: Ph3P; H2O / tetrahydrofuran
View Scheme
参考文献
Lowe 3rd., John A; Drozda, Susan E; Fisher, Katherine; Strick, Christine; Lebel, Lorraine; Schmidt, Christopher; Hiller, Donna; Zandi, Kathleen S
Bioorganic and medicinal chemistry letters, 2003 , vol. 13, # 7 p. 1291 - 1292
反应条件
1: NaN3
2: Ph3P; H2O / tetrahydrofuran
View Scheme
参考文献
Lowe 3rd., John A; Drozda, Susan E; Fisher, Katherine; Strick, Christine; Lebel, Lorraine; Schmidt, Christopher; Hiller, Donna; Zandi, Kathleen S
Bioorganic and medicinal chemistry letters, 2003 , vol. 13, # 7 p. 1291 - 1292
反应条件
1: 80 percent / ethanol; H2O / 20 °C
2: 46 percent / Pseudomonas cepacia lipase on modified ceramic particles / diisopropyl ether / 16 h / 27 °C
3: 88 percent / BH3*SMe2 / tetrahydrofuran / Heating
View Scheme
参考文献
Kamal, Ahmed; Khanna; Ramu
Tetrahedron Asymmetry, 2002 , vol. 13, # 18 p. 2039 - 2051
