(+)-顺式-2(r),3(s)-2,3-二羟基-2,3-二氢苯甲腈合成路线 (共 7 条)
反应条件
sodium hydroxide in water T=25°C; Kinetics; ConcentrationSolvent;
参考文献
Journal of the American Chemical Society, , vol. 134, # 34 p. 14056 - 14069,14
Journal of the American Chemical Society, , vol. 134, # 34 p. 14056 - 14069
反应条件
palladium on activated charcoal in methanol T=30°C; 1 h; atmospheric pressure;
参考文献
Advanced Synthesis and Catalysis, , vol. 349, # 4-5 p. 727 - 739
反应条件
toluene-4-sulfonic acid in N,N-dimethyl-formamide 20 h; Ambient temperature;
参考文献
Tran, Chuong Hao; Crout, David H.G.; Errington, William; Whited, Gregory M.
Tetrahedron Asymmetry, 1996 , vol. 7, # 3 p. 691 - 698
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
T=50°C; 4 h;
参考文献
Boyd, Derek R.; Sharma, Narain D.; Byrne, Breige; Hand, Mark V.; Malone, John F.; Sheldrake, Gary N.; Blacker, John; Dalton, Howard
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 12 p. 1935 - 1943
反应条件
1: toluene dioxygenase from intact cells of Pseudomonas putida UV4, O2
2: 52 percent / tetrakis(triphenylphosphine)palladium(0) / tetrahydrofuran / 45 h / 50 °C
View Scheme
参考文献
Boyd, Derek R.; Sharma, Narain D.; Byrne, Breige; Hand, Mark V.; Malone, John F.; Sheldrake, Gary N.; Blacker, John; Dalton, Howard
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 12 p. 1935 - 1943
反应条件
in ethanol
T=28°C; aq. culture of Pseudomonas putida UV4, pH ca. 7.5, 20percent aq. KOH;
参考文献
Blacker, A. John; Booth, R. John; Davies, Gareth M.; Sutherland, James K.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 22 p. 2861 - 2870
反应条件
cloned chlorobenzene dioxygenase in E. coli JM101 (pTEZ30); oxygen in methanol
T=30°C; pH=7.2; Kinetics; Further Variations:Reagents;
参考文献
Yildirim, Selcuk; Franko, Telma T.; Wohlgemuth, Roland; Kohler, Hans-Peter E.; Witholt, Bernard; Schmid, Andreas
Advanced Synthesis and Catalysis, 2005 , vol. 347, # 7-8 p. 1060 - 1072