1.1: n-BuLi; diisopropylamine / tetrahydrofuran; cyclohexane / 1 h / -78 °C 1.2: 88 percent / tetrahydrofuran; hexamethylphosphoric acid triamide; cyclohexane / 2 h / -78 °C 2.1: 83 percent / AlCl3 / chlorobenzene / 4 h / Heating View Scheme

1.1: lithium diisopropyl amide / tetrahydrofuran / 0.33 h / -78 °C / |Inert atmosphere 1.2: 2 h / -78 °C / |Inert atmosphere 2.1: AlCl3, aluminium chloride / chlorobenzene / 4 h / |Reflux 3.1: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 2 h / 20 °C 4.1: Fremy’s salt; sodium acetate / methanol; N,N-dimethyl-formamide; water / 14 h / 20 °C View Scheme

1.1: n-butyllithium; diisopropylamine / tetrahydrofuran / -78 °C / Inert atmosphere 1.2: 2 h / -78 °C / Inert atmosphere 2.1: AlCl3, aluminium chloride / chlorobenzene / 3.5 h / Reflux 3.1: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C / Cooling with ice View Scheme

1.1: n-butyllithium; diisopropylamine / tetrahydrofuran / -78 °C / Inert atmosphere 1.2: 2 h / -78 °C / Inert atmosphere 2.1: AlCl3, aluminium chloride / chlorobenzene / 3 h / Reflux 3.1: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C / Cooling with ice View Scheme