hydrogenchloride in acetone 72 h; Ambient temperature; Yield given;

1: 65 percent / H2SO4 / toluene / 2 h / Heating 2: 1.) BuLi, 2.) SO2, 3.) Cl2 / 1.) hexane, room temperature, 2 h, 2) -40 deg C to room temperature, overnight, 3.) H2O, 15 min 3: tetrahydrofuran / -10 - 20 °C 4: HCl / acetone / 72 h / Ambient temperature View Scheme

1: 1.) BuLi, 2.) SO2, 3.) Cl2 / 1.) hexane, room temperature, 2 h, 2) -40 deg C to room temperature, overnight, 3.) H2O, 15 min 2: tetrahydrofuran / -10 - 20 °C 3: HCl / acetone / 72 h / Ambient temperature View Scheme

1: tetrahydrofuran / -10 - 20 °C 2: HCl / acetone / 72 h / Ambient temperature View Scheme