(4S)-4-乙基-2-恶唑烷酮合成路线 （共 13 条）
反应条件
1: potassium fluoride on basic alumina / acetonitrile / 24 h / 20 °C
2: sodium periodate / methanol; water / 24 h / 0 - 20 °C
3: lithium hexamethyldisilazane / tetrahydrofuran / 5 h / -78 - 0 °C / Inert atmosphere
4: polystyrene supported PPh3 / toluene / 2 h / 100 °C
5: 5 Pd(II)/C(eggshell); hydrogen / ethanol / 24 h / 20 °C
View Scheme
参考文献
Gibson, Sarah; Jacobs, Hollie K.; Gopalan, Aravamudan S.
Tetrahedron Letters, 2011 , vol. 52, # 8 p. 887 - 890
参考文献
Najer et al.
Bulletin de la Societe Chimique de France, 1959 , p. 1609,1611,1841,1843
反应条件
n-butyllithium in tetrahydrofuran
T=-78°C;
参考文献
Neri, Claudia; Williams, Jonathan M. J.
Advanced Synthesis and Catalysis, 2003 , vol. 345, # 6-7 p. 835 - 848
