1.1: sodium / 0 °C 1.2: 1 h / 0 °C 1.3: 79 percent / conc. HCl / 0 °C / pH 1 2.1: 100 percent / diethylamine / palladium tetrakistriphenylphosphine / CH2Cl2 / 3 h / 20 °C View Scheme

1.1: sodium / 0 °C 1.2: 1 h / 0 °C 1.3: 79 percent / conc. HCl / 0 °C / pH 1 2.1: 100 percent / diethylamine / palladium tetrakistriphenylphosphine / CH2Cl2 / 3 h / 20 °C 3.1: 67 percent / tetramethylguanidine / dimethylsulfoxide / 9 h / 25 °C 4.1: tetrahydrofuran / 10.5 h / 0 - 25 °C 4.2: 123 g / ice / tetrahydrofuran / 3 h / 25 °C 5.1: 89 percent / aq. cesium carbonate / dimethylformamide / 5 h / 25 °C 6.1: 92 percent / aq. ammonium hydroxide / 3 h / 25 °C View Scheme

1.1: sodium / 0 °C 1.2: 1 h / 0 °C 1.3: 79 percent / conc. HCl / 0 °C / pH 1 2.1: 100 percent / diethylamine / palladium tetrakistriphenylphosphine / CH2Cl2 / 3 h / 20 °C 3.1: 100 percent / tetramethylguanidine / dimethylsulfoxide / 1 h / 25 °C View Scheme

1.1: sodium / 0 °C 1.2: 1 h / 0 °C 1.3: 79 percent / conc. HCl / 0 °C / pH 1 2.1: 100 percent / diethylamine / palladium tetrakistriphenylphosphine / CH2Cl2 / 3 h / 20 °C 3.1: 73 percent / sodium bicarbonate / H2O / 18 h / 25 °C View Scheme

1.1: sodium / 0 °C 1.2: 1 h / 0 °C 1.3: 79 percent / conc. HCl / 0 °C / pH 1 2.1: 100 percent / diethylamine / palladium tetrakistriphenylphosphine / CH2Cl2 / 3 h / 20 °C 3.1: 73 percent / tetramethylguanidine / dimethylsulfoxide / 1 h / 25 °C View Scheme