1: 3,4-dihydroxy-benzaldehyde With sodium hydride in N,N-dimethyl-formamide; mineral oil
T=20°C; 1 h; Inert atmosphereCooling with ice;
2: benzyl chloride in N,N-dimethyl-formamide; mineral oil
T=20°C; 18 h; Inert atmosphereCooling with ice;
参考文献
Zhang, Mingbao; Erik Jagdmann Jr.; Van Zandt, Michael; Beckett, Paul; Schroeter, Hagen
Tetrahedron Asymmetry, 2013 , vol. 24, # 7 p. 362 - 373
1: 3,4-dihydroxy-benzaldehyde With sodium hydride in N,N-dimethyl-formamide; mineral oil
T=0°C; 0.5 h; Inert atmosphere;
2: benzyl chloride in N,N-dimethyl-formamide; mineral oil
T=0°C; 12 h;
参考文献
NEUPROTECT PTY LTD; MCLACHLAN, Grant Andrew
Patent: WO2014/56038 A1, 2014 ;
Location in patent: Paragraph 123-125 ;
potassium carbonate in N,N-dimethyl-formamide
T=80°C; 24 h;
参考文献
Allwood, Billy L.; Kohnke, Franz H.; Slawin, Alexandra M. Z.; Stoddart, J. Fraser; Williams, David J.
Journal of the Chemical Society, Chemical Communications, 1985 , # 6 p. 311 - 314
Shoeib, Nagwa A.; Bibby, Michael C.; Blunden, Gerald; Linley, Peter A.; Swaine, David J.; Wheelhouse, Richard T.; Wright, Colin W.
Journal of Natural Products, 2004 , vol. 67, # 9 p. 1445 - 1449
